发明名称 |
Inhibidores de tipo bisamida de la señalización hedgehog |
摘要 |
The invention provides inhibitors of hedgehog signaling that are useful as a therapeutic agents for treating malignancies where the compounds have the general formula I: wherein ring A, ring B, R1, R2, R3, R4, R5, m and n are as defined herein. |
申请公布号 |
ES2604539(T3) |
申请公布日期 |
2017.03.07 |
申请号 |
ES20060844364T |
申请日期 |
2006.11.14 |
申请人 |
Genentech, Inc.;Curis, Inc. |
发明人 |
GOLDSMITH, Richard A.;SUTHERLIN, Daniel P.;ROBARGE, Kirk D.;OLIVERO, Alan G. |
分类号 |
C07D213/82;A61K31/44;A61K31/444;A61K31/4545;A61K31/496;A61P35/00;C07D231/14;C07D233/06;C07D239/28;C07D249/08;C07D265/36;C07D277/56;C07D285/06;C07D295/155;C07D333/38;C07D401/04;C07D401/12;C07D401/14;C07D417/12 |
主分类号 |
C07D213/82 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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