发明名称 Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith
摘要 Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed.
申请公布号 US9585892(B2) 申请公布日期 2017.03.07
申请号 US201414508967 申请日期 2014.10.07
申请人 Ambit Biosciences 发明人 Bhagwat Shripad S.;Lai Wei;Parent Stephan D.;Bevill Melanie J.;Schwartz Alan;Smolenskaya Valeriya N.
分类号 A61K31/185;A61K31/5377;C07D513/04 主分类号 A61K31/185
代理机构 Jones Day 代理人 Jones Day
主权项 1. A method of treating leukemia in a patient comprising administering to the patient a therapeutically effective amount of a solid form comprising a salt of the compound of formula (I): wherein the salt is selected from the group consisting of: hydrobromide, besylate, esylate, edisylate, mesylate, napsylate, sulfate and tosylate salts.
地址 San Diego CA US