发明名称 |
Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions thereof, and uses therewith |
摘要 |
Solid forms comprising N-(5-tert-butyl-isoxazol-3-yl)-N′-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea, compositions comprising the solid forms, methods of making the solid forms and methods of their use for the treatment of various diseases and/or disorders are disclosed. |
申请公布号 |
US9585892(B2) |
申请公布日期 |
2017.03.07 |
申请号 |
US201414508967 |
申请日期 |
2014.10.07 |
申请人 |
Ambit Biosciences |
发明人 |
Bhagwat Shripad S.;Lai Wei;Parent Stephan D.;Bevill Melanie J.;Schwartz Alan;Smolenskaya Valeriya N. |
分类号 |
A61K31/185;A61K31/5377;C07D513/04 |
主分类号 |
A61K31/185 |
代理机构 |
Jones Day |
代理人 |
Jones Day |
主权项 |
1. A method of treating leukemia in a patient comprising administering to the patient a therapeutically effective amount of a solid form comprising a salt of the compound of formula (I): wherein the salt is selected from the group consisting of: hydrobromide, besylate, esylate, edisylate, mesylate, napsylate, sulfate and tosylate salts. |
地址 |
San Diego CA US |