| 主权项 |
1. A compound of formula (I): wherein: T1 denotes one of the following groups: T2-W denotes one of the following groups: W denotes a single bond, or a group selected from —CHRc— and —CH═CH—; RW denotes H, Hal, linear or branched alkyl, or one of the following groups: or wherein Rb and Rw together with the nitrogen atom to which they are linked form one of the following groups: Rb denotes H or a linear or branched alkyl, or alternatively,
Rb and Rw together with the nitrogen atom to which they are linked form a Het group; Rc denotes H, Ar, or alkyl; Ra denotes H and a group selected from the following groups: Ar denotes one of the following groups optionally substituted with from 1 to 5 groups independently selected from Hal, CN, —CF3, —OCF3, O-alkyl, SO2-alkyl, COORb, —CO-alkyl, O-phenyl, SO2-phenyl, SO2—Het, O-Het, Het, —(CH2)n—Het, SO2—CF3, O—(CH2)n-Het, O—(CH2)n-alkyl, and A; Het denotes a monocyclic 5-8-membered ring being saturated, unsaturated or aromatic, containing 1 to 3 heteroatoms independently selected from N, O and S, or a group CO, and optionally substituted with from 1 to 5 groups independently selected from Hal, CN, —CF3, —OCF3, O-alkyl, SO2-alkyl, COORb, —CO-alkyl, O-phenyl, SO2-phenyl, SO2—CF3, O—(CH2)n-alkyl, SO2Ar, Ar, and A; A is branched or linear alkyl having 1 to 12 C-atoms, wherein one or more H atoms may be replaced by Ar, Het, Hal, ORb, COORb, CN or N(Rb)2 and wherein one or more CH2-groups may be replaced by O, CO, NRb, S, SO, SO2, phenyl, —CH═CH— or —C≡C— and/or by one of the following groups: having Hal or mesylate as counter ion; Hal denotes F, Cl, Br, or I; n is 1, 2 or 3; and pharmaceutically usable solvates, salts and stereoisomers thereof, including mixtures thereof in all ratios. |
