| 发明名称 |
Peptides Of Syndecan-1 For Inhibiting Angiogenesis |
| 摘要 |
The present invention provides a peptide derived from the extracellular domain of syndecan-1 that inhibits angiogenesis. |
| 申请公布号 |
US2017056470(A1) |
申请公布日期 |
2017.03.02 |
| 申请号 |
US201615347934 |
申请日期 |
2016.11.10 |
| 申请人 |
Wisconsin Alumni Research Foundation |
发明人 |
Rapraeger Alan C.;Beauvais DeannaLee M. |
| 分类号 |
A61K38/17;A61K45/06;C07K14/47 |
主分类号 |
A61K38/17 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a subject having a disease characterized by angiogenesis wherein the disease is not cancer, comprising contacting endothelial cells of the subject that express αVβ3 or αVβ5 integrin and are responsible for said angiogenesis with a peptide or polypeptide segment consisting of between 5 and 100 amino acid residues and comprising SEQ ID NO:21 or SEQ ID NO:13, whereby the disease is treated. |
| 地址 |
Madison WI US |
