发明名称 |
Novel chromone oxime derivative and its use as allosteric modulator of metabotropic glutamate receptors |
摘要 |
The present invention provides a novel chromone oxime derivative of formula (I), which is a modulator of nervous system receptors sensitive to glutamate and, furthermore, presents an advantageously high brain penetration upon oral administration. The invention also relates to a pharmaceutical composition containing this compound, and to its use for the treatment or prevention of conditions associated with altered glutamatergic signalling and/or functions, or conditions which can be affected by alteration of glutamate level or signalling, particularly acute and chronic neurological and/or psychiatric disorders. |
申请公布号 |
AU2015308438(A1) |
申请公布日期 |
2017.03.02 |
申请号 |
AU20150308438 |
申请日期 |
2015.08.27 |
申请人 |
Prexton Therapeutics SA |
发明人 |
Charvin, Delphine;Manteau, Baptiste;Pomel, Vincent;Conquet, Francois |
分类号 |
C07D495/04;A61K31/407;A61P25/16 |
主分类号 |
C07D495/04 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|