发明名称 METHODS FOR DIAGNOSIS AND PROGNOSIS OF INFLAMMATORY BOWEL DISEASE USING CYTOKINE PROFILES
摘要 The present invention relates to the field of inflammatory bowel disease. More specifically, the present invention relates to the use of cytokines to detect, diagnose, and assess inflammatory bowel disease. In one embodiment, a method for diagnosing Crohn's Disease (CD) in a patient comprises the steps of (a) collecting a sample from the patient; (b) measuring the levels of at least one cytokine in the sample collected from the patient; and (c) comparing the levels of the at least one cytokine with predefined cytokine levels, wherein a correlation between the cytokine levels in the patient sample and predefined cytokine levels indicates that the patient has CD. In a specific embodiment, the at least one cytokine comprises Interferon (IFN)-gamma, Interleukin (IL)-1beta, IL-6, IL-8, IL-12, IL-17 and CXCL10.
申请公布号 US2017059581(A1) 申请公布日期 2017.03.02
申请号 US201615258050 申请日期 2016.09.07
申请人 THE JOHNS HOPKINS UNIVERSITY ;Oklahoma Medical Research Foundation 发明人 Li Xuhang;Alex Philip J.;Centola Michael B.;Knowlton Nicholas
分类号 G01N33/68 主分类号 G01N33/68
代理机构 代理人
主权项
地址 Baltimore MD US