发明名称 ENANTIOMERS OF THE N-(2-AMINO-5-FLUORO-2-METHYLPENTYL)-8-[(2,6-DIFLUOROBENZYL)OXY]-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDE, AS WELL AS OF THE DI- AND TRIFLUORO DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES
摘要 The present application relates to novel 6-hydrogen-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders.
申请公布号 US2017057958(A1) 申请公布日期 2017.03.02
申请号 US201515308279 申请日期 2015.04.29
申请人 BAYER PHARMA AKTIENGESELLSCHAFT 发明人 Vakalopoulos Alexandros;Follmann Markus;Stasch Johannes-Peter;Brockschnieder Damian;Wunder Frank;Marquardt Tobias;Dietz Lisa;Mondritzki Thomas;Lang Dieter;Li Volkhart Min-Jian
分类号 C07D471/04;A61K45/06;A61K31/437 主分类号 C07D471/04
代理机构 代理人
主权项 1. Compound having the systematic name ent-N-(2-amino-5-fluoro-2-methylpentyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (enantiomer A) and the structural formula and the N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts thereof.
地址 Berlin, OT DE