发明名称 |
ENANTIOMERS OF THE N-(2-AMINO-5-FLUORO-2-METHYLPENTYL)-8-[(2,6-DIFLUOROBENZYL)OXY]-2-METHYLIMIDAZO[1,2-A]PYRIDINE-3-CARBOXAMIDE, AS WELL AS OF THE DI- AND TRIFLUORO DERIVATIVES FOR THE TREATMENT OF CARDIOVASCULAR DISEASES |
摘要 |
The present application relates to novel 6-hydrogen-substituted imidazo[1,2-a]pyridine-3-carboxamides, to processes for preparation thereof, to the use thereof, alone or in combinations, for treatment and/or prophylaxis of diseases, and to the use thereof for production of medicaments for treatment and/or prophylaxis of diseases, especially for treatment and/or prophylaxis of cardiovascular disorders. |
申请公布号 |
US2017057958(A1) |
申请公布日期 |
2017.03.02 |
申请号 |
US201515308279 |
申请日期 |
2015.04.29 |
申请人 |
BAYER PHARMA AKTIENGESELLSCHAFT |
发明人 |
Vakalopoulos Alexandros;Follmann Markus;Stasch Johannes-Peter;Brockschnieder Damian;Wunder Frank;Marquardt Tobias;Dietz Lisa;Mondritzki Thomas;Lang Dieter;Li Volkhart Min-Jian |
分类号 |
C07D471/04;A61K45/06;A61K31/437 |
主分类号 |
C07D471/04 |
代理机构 |
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代理人 |
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主权项 |
1. Compound having the systematic name ent-N-(2-amino-5-fluoro-2-methylpentyl)-8-[(2,6-difluorobenzyl)oxy]-2-methylimidazo[1,2-a]pyridine-3-carboxamide (enantiomer A) and the structural formula and the N-oxides, salts, solvates, salts of the N-oxides and solvates of the N-oxides and salts thereof. |
地址 |
Berlin, OT DE |