| 发明名称 |
PROCESS FOR THE PREPARATION OF 4-CARBONYL)AMINO]-3-FLUOROPHENOXY}-N-ETHYLPYRIDINE-2-CARBOXAMIDE, ITS SALTS AND MONOHYDRATE |
| 摘要 |
The present invention relates to a process for preparing 4-{4-[({[4-chloro-3-(trifluoromethyl)-phenyl]amino}carbonyl)amino]-3-fluorophenoxy}-N-methylpyridine-2-carboxamide, its salts and monohydrate. |
| 申请公布号 |
US2017057918(A1) |
申请公布日期 |
2017.03.02 |
| 申请号 |
US201615259576 |
申请日期 |
2016.09.08 |
| 申请人 |
BAYER INTELLECTUAL PROPERTY GMBH |
发明人 |
STIEHL Juergen;HEILMANN Werner;LÖGERS Michael;REHSE Joachim;GOTTFRIED Michael;WICHMANN Saskia |
| 分类号 |
C07D213/81 |
主分类号 |
C07D213/81 |
| 代理机构 |
|
代理人 |
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| 主权项 |
1. A process for preparing of the compound of the formula (I) its salt or monohydrate by treating the compound of the formula (IV) with the compound of formula (V) in a reaction mixture and thereafter the solved compound of the formula (I) is treated with an acid to form a salt of the compound of the formula (I) which precipitates from the solution containing the solved compound of the formula (I). |
| 地址 |
Monheim DE |
