THERAPEUTIC COMBINATIONS OF ORALLY ADMINISTERED PACLITAXEL AND A P-GP INHIBITOR FOR THE TREATMENT OF CANCER
摘要
The application pertains to pharmaceutical combinations of orally administered paclitaxel and a P-gp inhibitor. The pharmaceutical combinations are suitable for the treatment of cancer in a subject and for reducing or preventing toxicity, hypersensitivity -type infusion reactions, and other negative outcomes resulting from or associated with intravenously administered paclitaxel (e.g., Taxol® or paclitaxel formulated with Cremophor®) therapy in a subject suffering from cancer.
申请公布号
WO2017013490(A3)
申请公布日期
2017.03.02
申请号
WO2016IB01132
申请日期
2016.07.21
申请人
KINEX THERAPEUTICS (HK) LIMITED
发明人
KWAN, Min-fun, Rudolf;KRAMER, E., Douglas;FETTERLY, Geralk, J.;HUNG, Cheung-tak;JACKSON, Christopher Glyn Charles, Alexander;GLUE, Paul, William