发明名称 |
GAMMA-AAPEPTIDES WITH POTENT AND BROAD-SPECTRUM ANTIMICROBIAL ACTIVITY |
摘要 |
The present invention is directed to a novel class of antimicrobial agents called γ-AApeptides. The current invention provides various categories of γ-AApeptides, for example, linear γ-AApeptides, cyclic γ-AApeptides, and lipidated γ-AApeptides. γ-AApeptides of the current invention are designed to exert antimicrobial activity while being stable and non-toxic. γ-AApeptides also do not appear to lead to the development of microbial resistance in treated microorganisms. Thus, the disclosed γ-AApeptides can be used for the treatment of various medical conditions associated with pathogenic microorganisms. |
申请公布号 |
US2017058002(A1) |
申请公布日期 |
2017.03.02 |
申请号 |
US201615292162 |
申请日期 |
2016.10.13 |
申请人 |
CAI JIANFENG;NIU YOUHONG;WU HAIFAN;PADHEE SHRUTI |
发明人 |
CAI JIANFENG;NIU YOUHONG;WU HAIFAN;PADHEE SHRUTI |
分类号 |
C07K7/56;A61K47/48;C07K1/10;C07K7/06;C07K1/16 |
主分类号 |
C07K7/56 |
代理机构 |
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代理人 |
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主权项 |
1. (canceled) |
地址 |
TAMPA FL US |