METODO IN VITRO Y KIT PARA EL PRONOSTICO O PREDICCION DE LA RESPUESTA AL TRATAMIENTO CON AGENTES ANTIPSICOTICOS POR PARTE DE PACIENTES QUE HAN SUFRIDO UN PRIMER EPISODIO PSICOTICO

摘要

The present invention relates to an in vitro method for the prognosis or prediction of the response to treatment with anti-psychotic drugs in subjects who have suffered first episode psychosis (FEP), and specifically to the use of the expression value, in a biological sample isolated from said subjects, of the ratio formed by two of the isoforms – active isoform and truncated isoform – of the receptor (TrKB) of the nerve growth factor BDNF, named TrKB-FL and TrkB-T, respectively. The present invention also describes kits and uses of same to implement the method of the invention.