发明名称 METHODS OF REDUCING THE RISK OF A CARDIOVASCULAR EVENT IN A SUBJECT ON STATIN THERAPY
摘要 In various embodiments, the present invention provides methods of reducing the risk of a cardiovascular event in a subject on statin therapy and, in particular, a method of reducing the risk of a cardiovascular event in a subject on statin therapy having a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL, and administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of eicosapentaenoic acid ethyl ester or a derivative thereof.
申请公布号 US2017056361(A1) 申请公布日期 2017.03.02
申请号 US201615333968 申请日期 2016.10.25
申请人 Amarin Pharmaceuticals Ireland Limited 发明人 Soni Paresh
分类号 A61K31/232;A61K45/06;A61K31/397 主分类号 A61K31/232
代理机构 代理人
主权项 1. A method of reducing a risk of cardiovascular death and/or coronary revascularization in a subject on statin therapy, the method comprising administering to the subject a pharmaceutical composition comprising about 1 g to about 4 g of ethyl icosapentate per day, wherein the subject has a fasting baseline triglyceride level of about 135 mg/dL to about 500 mg/dL and optionally has established cardiovascular disease.
地址 Dublin IE