发明名称 気道感染症の予防及び/又は治療のためのヒト呼吸器合胞体ウイルス(hRSV)に指向性を有する改良アミノ酸配列及びこれを含むポリペプチド
摘要 Amino acid sequences are provided that are directed against and/or that can specifically bind protein F of hRSV, as well as to compounds or constructs, and in particular proteins and polypeptides, that comprise or essentially consist of one or more such amino acid sequences. The amino acid sequences, polypeptides and therapeutic compounds and compositions provided by the invention show an improved stability, less immunogenicity and/or improved affinity and/or avidity for protein F of hRSV. The invention also relates to the uses of such amino acid sequences, polypeptides, compounds or constructs for prophylactic and/or therapeutic purposes.
申请公布号 JP6081196(B2) 申请公布日期 2017.03.01
申请号 JP20120513641 申请日期 2010.06.07
申请人 アブリンクス エン.ヴェー. 发明人 デプラ,エリク;ストーテラーズ,カテリーネ;スタエレンス,ステファニー
分类号 C12N15/09;A61K38/16;A61K48/00;A61P11/00;A61P11/06;A61P31/14;C07K16/10;C12N1/15;C12N1/19;C12N1/21;C12N5/10 主分类号 C12N15/09
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