发明名称 DIOXINO- AND OXAZIN-[2,3-D]PYRIMIDINE PI3K INHIBITOR COMPOUNDS AND METHODS OF USE
摘要 Dioxino- and oxazin-[2,3-d]pyrimidine PI3K inhibitor compounds of Formula I with anti-cancer activity, anti-inflammatory activity, or immunoregulatory properties, and more specifically with PI3 kinase modulating or inhibitory activity are described. Methods are described for using the tricyclic PI3K inhibitor compounds of Formula I for in vitro, in situ, and in vivo diagnosis or treatment of mammalian cells, organisms, or associated pathological conditions.
申请公布号 EP2890698(B1) 申请公布日期 2017.03.01
申请号 EP20130753637 申请日期 2013.08.29
申请人 F. Hoffmann-La Roche AG 发明人 HEALD, Robert Andrew;MCLEAN, Neville James
分类号 C07D491/04;A61K31/519;A61K31/527;A61K31/5383;A61K31/5386;A61P29/00;A61P35/00;C07D498/04 主分类号 C07D491/04
代理机构 代理人
主权项
地址
您可能感兴趣的专利