发明名称 |
ANTI-CMET ANTIBODY |
摘要 |
The disclosure relates to an antibody capable of binding specifically to the human c-Met receptor and/or capable of specifically inhibiting the tyrosine kinase activity of said receptor, with an improved antagonistic activity, said antibody comprising a modified hinge region. The disclosure also relates to a composition comprising such an antibody antagonist to c-Met and its use as a medicament for treating cancer. |
申请公布号 |
EP3135691(A1) |
申请公布日期 |
2017.03.01 |
申请号 |
EP20160192250 |
申请日期 |
2009.12.02 |
申请人 |
PIERRE FABRE MEDICAMENT |
发明人 |
GOETSCH, Liliane;WURCH, Thierry;BES, Cédric |
分类号 |
C07K16/28;A61K39/395;A61P35/00;C07K16/00;C07K16/46 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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