IMPROVED PROCESSES FOR THE PREPARATION OF 1-ARYL-5-ALKYL PYRAZOLE COMPOUNDS
摘要
Provided are improved processes for the preparation of 1-aryl pyrazole compounds of formula (I) and (IB): which are substituted at the 5-position of the pyrazole ring with a carbon-linked functional group. The process described are efficient and scalable and do not utilize hazardous sulfenyl halide reagents.
申请公布号
EP2852577(B1)
申请公布日期
2017.03.01
申请号
EP20130720198
申请日期
2013.04.22
申请人
Merial, Inc.
发明人
MENG, Charles, Q.;LE HIR DE FALLOIS, Loic, Patrick;LEE, Hyoung, Ik;ZHAN, Xinxi;LABROSSE, Jean-Robert;MULHAUSER, Michel