发明名称 MACROCYCLIC COMPOUNDS USEFUL AS PHARMACEUTICALS
摘要 The present invention provides compounds having formula (I), and additionally provides methods for the synthesis thereof and methods for the use thereof in the treatment of various disorders including inflammatory or autoimmune disorders, and disorders involving malignancy or increased angiogenesis, wherein R 1 -R 11 , t, X, Y, Z and n are as defined herein.
申请公布号 EP2308861(B1) 申请公布日期 2017.03.01
申请号 EP20100075633 申请日期 2003.03.07
申请人 Eisai R&D Management Co., Ltd. 发明人 Boivin, Roch;Chiba, Kenichi;Muramoto, Kenzo;Shirota, Hiroshi;Du, Hong;Eguchi, Yoshihito;Fujita, Masanori;Gusovsky, Fabian;Goto, Masaki;Harmange, Jean-Christophe;Inoue, Atsushi;Jiang, Yimin;Kawada, Megumi;Kawai, Takatoshi;Kawakami, Yoshiyuki;KIMURA, Akifumi;Kotake, Makoto;Kuboi, Yoshikazu;Lemelin, Charles-André;Li, Xiang-Yi;Matsushima, Tomohiro;Mizui, Yoshiharu;Sakurai, Hideki;Chow, Jesse;Shen, Yong-Chun;Spyvee, Mark;Tanaka, Isao;Wang, John (Yuan);Yamamoto, Satoshi;Yoneda, Naoki
分类号 C07D313/00;C07D491/044;A61K31/335;A61K31/36;A61K31/365;A61K31/395;A61K31/4178;A61K31/4188;A61K31/5377;A61P1/00;A61P1/04;A61P1/16;A61P3/10;A61P7/04;A61P9/00;A61P9/10;A61P11/00;A61P11/02;A61P11/06;A61P17/00;A61P17/04;A61P17/06;A61P17/16;A61P19/02;A61P19/04;A61P19/10;A61P21/04;A61P25/00;A61P25/02;A61P25/08;A61P25/28;A61P27/02;A61P29/00;A61P31/04;A61P31/18;A61P33/06;A61P35/00;A61P37/02;A61P37/06;A61P37/08;A61P43/00;C07D225/06;C07D267/00;C07D401/12;C07D405/12;C07D407/12;C07D491/04;C07D493/04;C07D521/00 主分类号 C07D313/00
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