发明名称 5-PHENYL-[1,2,4]TRIAZOLO[1,5-A]PYRIDIN-2-YL CARBOXAMIDES AS JAK INHIBITORS
摘要 A novel compound able to inhibit JAK is disclosed, that comprises a compound according to Formula I: or a pharmaceutically acceptable salt thereof. The compound may be prepared as a pharmaceutical composition, and may be used for the treatment of a variety of conditions in mammals including humans, including by way of non-limiting example, inflammatory conditions, autoimmune diseases, proliferative diseases, transplantation rejection, diseases involving impairment of cartilage turnover, congenital cartilage malformations, and/or diseases associated with hypersecretion of IL6.
申请公布号 EP2445911(B1) 申请公布日期 2017.03.01
申请号 EP20100724881 申请日期 2010.06.25
申请人 Galapagos N.V. 发明人 MENET, Christel Jeanne Marie;SMITS, Koen Kurt
分类号 A61K45/06;A61K31/541;C07D471/04 主分类号 A61K45/06
代理机构 代理人
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