IMPROVED METHOD FOR RECONSTRUCTING A NON-HUMAN ANIMAL EMBRYO

摘要

The present invention refers to a method for reconstructing a non-human animal embryo, to a method for generating a non-human animal and to a non-human animal or non-human animal reconstructed embryo obtainable by the methods according to the invention. The method of somatic cell nuclear transfer (SCNT) comprises a step of transiently expressing or inducing the uptake of a protein involved in male sperm maturation, such as protamine or transition protein, in the somatic donor cell before nuclear transfer.