发明名称 NOVEL DISUBSTITUTED 1, 2, 4-TRIAZINE COMPOUND
摘要 This invention provides a novel disubstituted 1,2,4-triazine compound or a pharmaceutically acceptable salt thereof, which has an aldosterone synthetase inhibitory activity and is useful for preventing and/or treating various diseases or conditions associated with aldosterone; a method for preparing it; use of it; as well as a pharmaceutical composition comprising it as an active ingredient. A compound of the general formula [I]: wherein R A is, for example, a group of the following formula (A-1): wherein ring A 1 is, for example, a cycloalkyl group which may be substituted, and R B is, for example, a monocyclic cycloalkyl group, or a pharmaceutically acceptable salt thereof.
申请公布号 EP3135668(A1) 申请公布日期 2017.03.01
申请号 EP20150782458 申请日期 2015.04.23
申请人 Mitsubishi Tanabe Pharma Corporation 发明人 USHIROGOCHI, Hideki;SASAKI, Wataru;ONDA, Yuichi;SAKAKIBARA, Ryo;AKAHOSHI, Fumihiko
分类号 C07D253/06;A61K31/53;A61K31/5377;A61K31/541;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P35/00;C07D401/04;C07D401/12;C07D401/14;C07D403/04 主分类号 C07D253/06
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