发明名称 |
NOVEL DISUBSTITUTED 1, 2, 4-TRIAZINE COMPOUND |
摘要 |
This invention provides a novel disubstituted 1,2,4-triazine compound or a pharmaceutically acceptable salt thereof, which has an aldosterone synthetase inhibitory activity and is useful for preventing and/or treating various diseases or conditions associated with aldosterone; a method for preparing it; use of it; as well as a pharmaceutical composition comprising it as an active ingredient. A compound of the general formula [I]:
wherein R A is, for example, a group of the following formula (A-1):
wherein ring A 1 is, for example, a cycloalkyl group which may be substituted,
and R B is, for example, a monocyclic cycloalkyl group,
or a pharmaceutically acceptable salt thereof. |
申请公布号 |
EP3135668(A1) |
申请公布日期 |
2017.03.01 |
申请号 |
EP20150782458 |
申请日期 |
2015.04.23 |
申请人 |
Mitsubishi Tanabe Pharma Corporation |
发明人 |
USHIROGOCHI, Hideki;SASAKI, Wataru;ONDA, Yuichi;SAKAKIBARA, Ryo;AKAHOSHI, Fumihiko |
分类号 |
C07D253/06;A61K31/53;A61K31/5377;A61K31/541;A61P9/00;A61P9/04;A61P9/08;A61P9/10;A61P9/12;A61P13/12;A61P25/00;A61P35/00;C07D401/04;C07D401/12;C07D401/14;C07D403/04 |
主分类号 |
C07D253/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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