发明名称 BIOMOLECULE-RELEASING CELL AND SELECTION THEREOF BY MEANS OF A SURFACE PROTEIN
摘要 The invention relates, firstly, to a biomolecule-releasing cell characterised by a surface protein with an extracellularly exposed ligation peptide sequence for enzymatic conjugation of an adapter ligand, said adapter ligand being suitable for the indirect or direct coupling of a molecular catcher structure which has at least one specific binding site for the released biomolecules and which is at a distance from the specific binding site, secondly, to a method for selecting such a cell, and thirdly, to a means for this method comprising the surface protein that is characterised by an extracellularly exposable ligation peptide sequence for enzymatic conjugation of an adapter ligand, a nucleic acid coding for the surface protein, an expression vector for the nucleic acid, and a cell containing the expression vector.
申请公布号 EP3134435(A1) 申请公布日期 2017.03.01
申请号 EP20140727392 申请日期 2014.04.20
申请人 New/era/mabs GmbH 发明人 LISTEK, Martin;HANACK, Katja;MICHEEL, Burkhard
分类号 C07K14/71;C07K16/00;C12N5/00;C12N5/16;C12N15/63;G01N33/50;G01N33/531;G01N33/569 主分类号 C07K14/71
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