Selective recruitment and activation of fiber types in nerves for the control of undesirable brain state changes

摘要

We disclose methods and medical device systems for selectively recruiting a nerve fiber type within a cranial nerve, a peripheral nerve or a spinal root. Such a method may comprise applying a first pressure, a heating, and/or a cooling to a second location of the nerve, the pressure, heating, or cooling sufficient to substantially block at least one of activation or conduction in at least one fiber population through the second location of the nerve for a blocking time period; and applying an electrical signal to a first location during the blocking time period.

主权项

1. A method for selectively recruiting a nerve fiber type of a cranial nerve, a peripheral nerve or a spinal root, comprising:
performing an operation selected from one of heating or cooling a second location of said cranial nerve, said peripheral nerve or said spinal root, said heating or cooling sufficient to temporarily and substantially block at least one of activation or conduction on at least a first fiber type of said cranial nerve, said peripheral nerve or said spinal root for a blocking time period; and applying an electrical neurostimulation signal to a first location of said cranial nerve, said peripheral nerve or said spinal root during said blocking time period.