发明名称 PROCESS FOR THE PREPARATION OF PEMETREXED AND LYSIN SALT THEREOF
摘要 The present invention refers to a process for the synthesis of pemetrexed and salts thereof, in particular to a lysine salt thereof, to said salt as such and to pharmaceutical compositions that comprise the same. Furthermore, the present disclosure also relates to a crystalline form of the synthesis intermediate pemetrexed diethyl ether and a crystalline form of the pemetrexed lysine salt.
申请公布号 SI2882753(T1) 申请公布日期 2017.02.28
申请号 SI20130030427 申请日期 2013.08.08
申请人 Berlin-Chemie AG 发明人 BONACCORSI Fabrizio;CALVANI Federico;PASQUI Franco
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