| 发明名称 | Antibody specifically binding to ANG2 and use thereof | ||
| 摘要 | An Ang2 specific antibody, a method of preventing and/or treating a disease related to the activation and/or overproduction (overexpression) of Ang2 by administering the antibody to a subject, and a method of screening a candidate substance for diagnosing, preventing, or treating a disease related to activation or overproduction of Ang2. | ||
| 申请公布号 | US9580497(B2) | 申请公布日期 | 2017.02.28 |
| 申请号 | US201514606441 | 申请日期 | 2015.01.27 |
| 申请人 | SAMSUNG ELECTRONICS CO., LTD. | 发明人 | Kim Kyung Eun;Lee Yoon Sook;Han Sang Yeul;Kim Hyung-Chan;Lee Kwang Hoon;Lee Hyo Seon;Kim Seok Kyun |
| 分类号 | A61K39/395;C07K16/00;C07K16/28;C07K16/22;G01N33/68;C07K16/30;A61K39/00 | 主分类号 | A61K39/395 |
| 代理机构 | Leydig, Voit & Mayer, Ltd. | 代理人 | Leydig, Voit & Mayer, Ltd. |
| 主权项 | 1. An anti-Ang2 antibody or an antigen-binding fragment thereof, comprising a heavy chain variable region comprising a polypeptide (CDR-H1) comprising SEQ ID NO: 4, a polypeptide (CDR-H2) comprising SEQ ID NO: 8, and a polypeptide (CDR-H3) comprising SEQ ID NO: 12; and a light chain variable region comprising a polypeptide (CDR-L1) comprising SEQ ID NO: 16, a polypeptide (CDR-L2) comprising SEQ ID NO: 20, and a polypeptide (CDR-L3) comprising SEQ ID NO: 24. | ||
| 地址 | Suwon-si KR | ||