Pyrrolo[2,3-D]pyrimidine derivatives as CB2 receptor agonists

摘要

The invention relates to a compound of formula (I);wherein A and R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

主权项

1. A compound of formula (I) wherein A is CH2 or absent; R1 and R2, together with the nitrogen atom to which they are attached form substituted pyrrolidinyl or 2-oxa-6-azaspiro[3.3]heptyl, wherein substituted pyrrolidinyl is pyrrolidinyl substituted with one or two substituents independently selected from halogen, hydroxyl and alkylcarbonyloxy; and R3 is halophenyl, alkylsulfonylphenyl, haloalkylphenyl, halopyridinyl, alkyloxadiazolyl, alkyltriazolyl, alkyltetrazolyl, oxolanyl, cycloalkyltetrazolyl or haloalkyl-1H-pyrazolyl; or a pharmaceutically acceptable salt or ester thereof.