A PLURISUBSTITUTED HYDROXYAPATITE AND THE COMPOSITE THEREOF WITH A NATURAL AND/OR SYNTHETIC POLYMER, THEIR PREPARATION AND USES THEREOF

摘要

The present invention relates to a hydroxyapatite multi-substituted with, physiologically compatible ion species and to its biohybrid composite with a natural and/or synthetic polymer, which are useful in the preparation of a biomimetic bone substitute for treating bone tissue defects. Furthermore, the present invention relates to a method for their preparation and uses.