发明名称 Derivados de 3,4-dihidropirrolo[1,2-a]pirazina-2,8(1H)-dicarboxamida, su preparación y uso terapéutico de los mismos
摘要 Compounds corresponding to the general formula (I) wherein R2 represents a group C1-10-alkyl, C3-10-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-alkyl-C3-7-cycloalkyl, C3-7-cycloalkyl-C3-7-cycloalkyl, C1-6-alkylthio-C-1-10-alkyl, C1-6-alkoxy-C1-10-alkyl, hydroxy-C1-10-alkyl, hydroxy-C1-6-alkyl-C3-7-cycloalkyl-C1-6-alkyl, hydroxy-C3-10-cycloalkyl, C1-10-fluoroalkyl or C3-10-fluorocycloalkyl; an optionally substituted heterocyclic group; a group C1-10-alkyl substituted with an optionally substituted heterocyclic group; X6 represents a group chosen from hydrogen, fluorine, chlorine and bromine atoms or a group C1-6-alkyl, C3-7-cycloalkyl, C3-7-cycloalkyl-C1-6-alkyl, C1-6-fluoroalkyl or cyano; and R7 represents an aryl group such as phenyl or naphthyl, optionally substituted with one or more substituents, in the form of the base or of an acid-addition salt, and the therapeutic use thereof.
申请公布号 ES2603420(T3) 申请公布日期 2017.02.27
申请号 ES20110781590T 申请日期 2011.06.01
申请人 SANOFI 发明人 COTE-DES-COMBES, Sylvain;FROISSANT, Jacques;GIBERT, Jean-François;MARGUET, Frank;PACAUD, Christophe;PUECH, Frédéric;RAVET, Antoine
分类号 C07D487/04;A61K31/4985;A61P9/00;A61P25/00;A61P25/28;A61P29/00;C07D207/337;C07D241/06 主分类号 C07D487/04
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