发明名称 |
NOVEL GLP-1 RECEPTOR MODULATORS |
摘要 |
Compounds are provided that modulate the glucagon-like peptide 1 (GLP-1) receptor, as well as methods of their synthesis, and methods of their therapeutic and/or prophylactic use. Such compounds can act as modulators or potentiators of GLP-1 receptor on their own, or with incretin peptides such as GLP-1(7-36), GLP-1(9-36), and oxyntomodulin, or with peptide-based therapies, such as exenatide and liraglutide, and have the following general structure (where “” represents either or both the R and S form of the compound): where A, B, C, R1, R2, R3, R4, R5, n, p and q are as defined herein. |
申请公布号 |
SG11201700364P(A) |
申请公布日期 |
2017.02.27 |
申请号 |
SG11201700364P |
申请日期 |
2015.07.24 |
申请人 |
CELGENE INTERNATIONAL II SARL |
发明人 |
BOEHM, MARCUS, F.;MARTINBOROUGH, ESTHER;MOORJANI, MANISHA;TAMIYA, JUNKO;HUANG, LIMING;YEAGER, ADAM R.;BRAHMACHARY, ENUGURTHI;FOWLER, THOMAS;NOVAK, ANDREW;MEGHANI, PREMJI;KNAGGS, MICHAEL |
分类号 |
C07D403/06;A61K31/506;A61P3/00;C07D403/10;C07D403/14;C07D409/12;C07D409/14 |
主分类号 |
C07D403/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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