摘要 |
Disclosed rifaximin:piperazine cocrystal 1, having an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ (+/- 0.10 degree θ) at 5.74, 6.58, 7.49, 8.21, and 9.83. Also disclosed is a rifaximin:piperazine cocrystal 2, having an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ (+/- 0.10 degree θ) at 3.64, 5.58, 6.45, 7.29, 7.60, 8.27, and 9.01. Also disclosed is a pharmaceutical composition comprising a rifaximin:piperazine cocrystal as defined above and a pharmaceutically acceptable carrier. |