发明名称 New forms of rifaximin and uses thereof
摘要 Disclosed rifaximin:piperazine cocrystal 1, having an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ (+/- 0.10 degree θ) at 5.74, 6.58, 7.49, 8.21, and 9.83. Also disclosed is a rifaximin:piperazine cocrystal 2, having an X-ray powder diffraction pattern having characteristic peaks expressed in degrees 2θ (+/- 0.10 degree θ) at 3.64, 5.58, 6.45, 7.29, 7.60, 8.27, and 9.01. Also disclosed is a pharmaceutical composition comprising a rifaximin:piperazine cocrystal as defined above and a pharmaceutically acceptable carrier.
申请公布号 NZ710780(A) 申请公布日期 2017.02.24
申请号 NZ20110710780 申请日期 2011.06.03
申请人 SALIX PHARMACEUTICALS LTD. 发明人 Parent Stephan D.;Schultheiss Nathan Carl;Wu Yiduo;Bevill Melanie Janelle;Houston Travis L.;Vlahova Petinka
分类号 C07D498/16;A61K31/4188;A61K31/437;C07D498/00;C07D498/22 主分类号 C07D498/16
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