发明名称 |
RECOMBINANT POLYPEPTIDE PRODUCTION |
摘要 |
Disclosed herein is a method for producing a recombinant polypeptide in a mammalian cell culture in which the mammalian cells have a modified microRNA activity level. In one embodiment, a microRNA activity level is increased. In another embodiment, a microRNA activity level is decreased. In a more particular embodiment, the mammalian cells have a reduced miRNA-let-7a activity level. |
申请公布号 |
HK1218562(A1) |
申请公布日期 |
2017.02.24 |
申请号 |
HK20160106504 |
申请日期 |
2016.06.07 |
申请人 |
MEDIMMUNE LLC |
发明人 |
STREICHER, Katie K;JACOBS, Jonathan J;GEORGANTAS III, Robert, W. RW;GREENLEES, Lydia L;RANADE, Koustubh K;BOWEN, Michael M |
分类号 |
C12P;C12N |
主分类号 |
C12P |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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