发明名称 |
MODIFIED SINGLE DOSE, MICROPLEGIC APPROACH TO CARDIOPLEGIA FOR ADULT HEART |
摘要 |
Disclosed are compositions and methods for providing a modified single dose all blood approach to cardioplegia and reanimation. The disclosed method of preserving a heart comprises of administering a cardiac arrest induction solution to the blood of a subject, perfusing the heart with the blood containing the cardiac arrest induction solution, and reanimating the heart with a cardiac reanimation solution. The cardiac arrest induction solution disclosed herein consists essentially of Potassium, a calcium channel blocker, a sodium channel blocker, and a free radical scavenger, while the cardiac reanimation solution comprises of calcium channel blocker and one or more of a sodium channel blocker, a beta receptor blocker, potassium, and a buffer. |
申请公布号 |
US2017049811(A1) |
申请公布日期 |
2017.02.23 |
申请号 |
US201515308269 |
申请日期 |
2015.05.01 |
申请人 |
Berry Catherine E.;Kalin Candice |
发明人 |
Berry Catherine E.;Kalin Candice |
分类号 |
A61K33/06;A61K31/216;A61K31/047;A61K9/08;A61K33/00;A61K31/167 |
主分类号 |
A61K33/06 |
代理机构 |
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代理人 |
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主权项 |
1. A cardiac arrest induction solution consisting essentially of Potassium, Lidocaine, Magnesium, and Mannitol. |
地址 |
Atlanta GA US |