发明名称 |
LIQUID FORMULATIONS CONTAINING PICOSULFATE AND MAGNESIUM CITRATE |
摘要 |
Liquid formulations containing picosulfate and magnesium citrate are provided. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery. |
申请公布号 |
US2017049758(A1) |
申请公布日期 |
2017.02.23 |
申请号 |
US201615238408 |
申请日期 |
2016.08.16 |
申请人 |
FERRING B.V. |
发明人 |
Liang Alfred Chi-Yeh;Patel Nipul Ghanshyambhai;Li Jian-Xin;Larsen Crilles Casper |
分类号 |
A61K31/4402;A61K9/08;A61K47/02;A61K31/194;A61K47/36;A61K47/38;A61K47/12;A61K33/08 |
主分类号 |
A61K31/4402 |
代理机构 |
|
代理人 |
|
主权项 |
1. A liquid formulation comprising:
sodium picosulfate; magnesium citrate; and at least one precipitation inhibitor, wherein the precipitation inhibitor is a carboxylic acid, an ammonium salt or a soluble anionic polymer; wherein the precipitation inhibitor is malonic acid or tartaric acid if the formulation does not comprise an ammonium salt or a soluble anionic polymer; wherein the formulation is in the form of an aqueous solution having a pH in the range from about 4.0 to about 6.5. |
地址 |
Hoofddorp NL |