发明名称 LIQUID FORMULATIONS CONTAINING PICOSULFATE AND MAGNESIUM CITRATE
摘要 Liquid formulations containing picosulfate and magnesium citrate are provided. The formulations are useful to treat constipation or for the clearance of the bowel prior to X-ray examination, endoscopy or surgery.
申请公布号 US2017049758(A1) 申请公布日期 2017.02.23
申请号 US201615238408 申请日期 2016.08.16
申请人 FERRING B.V. 发明人 Liang Alfred Chi-Yeh;Patel Nipul Ghanshyambhai;Li Jian-Xin;Larsen Crilles Casper
分类号 A61K31/4402;A61K9/08;A61K47/02;A61K31/194;A61K47/36;A61K47/38;A61K47/12;A61K33/08 主分类号 A61K31/4402
代理机构 代理人
主权项 1. A liquid formulation comprising: sodium picosulfate; magnesium citrate; and at least one precipitation inhibitor, wherein the precipitation inhibitor is a carboxylic acid, an ammonium salt or a soluble anionic polymer; wherein the precipitation inhibitor is malonic acid or tartaric acid if the formulation does not comprise an ammonium salt or a soluble anionic polymer; wherein the formulation is in the form of an aqueous solution having a pH in the range from about 4.0 to about 6.5.
地址 Hoofddorp NL