| 发明名称 |
MOLECULAR ACTIVATORS OF THE WNT/BETA-CATENIN PATHWAY |
| 摘要 |
The present invention is directed toward a method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling by selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. A method of similarly modulating the Wnt/β-catenin pathway in a subject is also discussed. |
| 申请公布号 |
US2017049793(A1) |
申请公布日期 |
2017.02.23 |
| 申请号 |
US201514701936 |
申请日期 |
2015.05.01 |
| 申请人 |
Moon Randall T.;Biechele Travis L.;Camp Nathan D.;Haggarty Stephen;Fass Daniel |
发明人 |
Moon Randall T.;Biechele Travis L.;Camp Nathan D.;Haggarty Stephen;Fass Daniel |
| 分类号 |
A61K31/708;A61K31/353;A61K31/7048;A61K31/357;A61K31/506;A61K31/4406;A61K31/167;A61K31/196;A61K31/24;A61K31/4409;A61K31/472;A61K31/5377;A61K31/69;A61K31/15;A61K31/495;A61K31/426;A61K31/52;A61K31/404;A61K31/405;A61K31/4178;A61K31/4439;A61K31/047;A61K31/695;A61K31/407;A61K31/403;A61K31/421;A61K31/5383;A61K31/351;A61K31/4152;A61K31/166;A61K31/585;A61K31/57;A61K31/565;A61K31/365;A61K31/201;A61K31/336;A61K31/4402;A61K31/015;A61K31/366;A61K31/553;A61K31/5575;A61K31/55;A61K31/27;A61K31/4245;A61K31/352 |
主分类号 |
A61K31/708 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
1. A method of treating a subject for a condition mediated by aberrant Wnt/β-catenin signaling, said method comprising:
selecting a subject with a condition mediated by aberrant Wnt/β-catenin signaling and administering to the selected subject a compound selected from the group consisting of those set forth in Table 1, Table 2, and a pharmaceutically acceptable salt thereof. |
| 地址 |
Kenmore WA US |
