COMBINATION CANCER TREATMENT

摘要

Described herein is TRAIL receptor targeting therapy in combination with metformin for treatment of cancer in humans. Using TRAIL receptor targeting therapy such as the TRAIL molecule, agonistic human monoclonal antibodies against TRAIL receptors, or peptides targeting TRAIL receptors in combination with metformin for the treatment of all types of cancer allows to obtain an optimum therapeutical effect at any time of the progression of the disease.

主权项

1. A method of treating cancer in a human individual in need of treatment for cancer, comprising co-administering metformin and a TRAIL receptor agonist, wherein the metformin is administered in an effective amount to sensitize cancer cells to the TRAIL receptor agonist.