主权项 |
1. A differentiation-inducing composition for inducing cell differentiation,
the differentiation-inducing composition comprising: a degradation product of a collagen or an atelocollagen, the degradation product containing at least a portion of a triple helical domain of the collagen or the atelocollagen, the degradation product resulting from cleavage of a chemical bond between X1 and X2, between X2 and G, or between X4 and G in an amino acid sequence in (1) below within the triple helical domain, cleavage of a chemical bond between X1 and X2, between X2 and G, between X4 and G, between G and X7, or between X14 and G in an amino acid sequence in (2) below within the triple helical domain, or cleavage of a chemical bond between Y1 and Y2 in an amino acid sequence in (3) below at an amino terminus of the triple helical domain, the amino acid sequence in (1) or (2) being at an amino terminus of the triple helical domain, (1) -G-X1-X2-G-X3-X4-G-X5-X6-G-, (2) -G-X1-X2-G-X3-X4-G-X5-X6-G-X7-X8-G-X9-X10-G-X11-X12-G-X13-X14-G-, (3) -Y1-Y2-Y3-G-Y4-Y5-G-Y6-Y7-G-Y8-Y9-G-, where G represents glycine, and X1 to X14 and Y1 to Y9 each represent an amino acid. |