发明名称 HYDROXYTRIAZINE COMPOUND AND MEDICAL USE THEREOF
摘要 The present invention provides a compound that has inhibiting activity against mPGES-1 and is useful in the prevention or treatment of pain, rheumatoid arthritis, osteoarthritis, fever, Alzheimer's disease, multiple sclerosis, arteriosclerosis, glaucoma, ocular hypertension, ischemic retinoapthy, systemic scleroderma and/or malignant tumor such as colon cancer. The present invention relates to the compound of formula [I-a], [I-b], or [I-c] or a pharmaceutically acceptable salt thereof. (Each symbol in the formulas is as defined in the description.)
申请公布号 WO2017030115(A1) 申请公布日期 2017.02.23
申请号 WO2016JP73879 申请日期 2016.08.16
申请人 JAPAN TOBACCO INC. 发明人 MITANI, Ikuo;HIRONO, Yutaro;YAMASHITA, Masaki
分类号 C07D251/22;A61K31/53;A61K45/00;A61P9/10;A61P17/00;A61P19/02;A61P25/00;A61P25/04;A61P25/28;A61P27/02;A61P27/06;A61P29/00;A61P35/00;A61P43/00;C07D401/04 主分类号 C07D251/22
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