发明名称 |
IMMUNOASSAY AND ANTIBODIES FOR THE DETECTION OF CHROMOGRANIN A |
摘要 |
The present invention relates to an immunoassay method for the detection of Chromogranin A (or fragment(s) thereof) comprising the steps of contacting a sample suspected of comprising Chromogranin A with a first antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A and a second antibody or an antigen-binding fragment or derivative thereof specific for Chromogranin A under conditions allowing for the formation of a ternary complex between Chromogranin A and the two antibodies or antigen-binding fragments or derivates thereof, and detecting the binding of the two antibodies or antigen-binding fragments or derivates thereof to Chromogranin A. Also provided are antibodies directed against amino acid residues 124 to 144 and 280 to 301 of Chromogranin A and their use in the immunoassay method. |
申请公布号 |
EP3132268(A1) |
申请公布日期 |
2017.02.22 |
申请号 |
EP20150715739 |
申请日期 |
2015.04.14 |
申请人 |
Cézanne S.A.S. |
发明人 |
CARUHEL, Pascaline;RIGAULT, Valérie;GUÉRIN, Nadine |
分类号 |
G01N33/577;C07K16/18 |
主分类号 |
G01N33/577 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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