发明名称 自己ゲル化核酸
摘要 The purpose of the invention of the present application is to provide a method for preparing a hydrogel composed substantially only of nucleic acids. The invention of the present application provides: a nucleic acid sol-like composition for producing a nucleic acid gel without requiring the use of any nucleic acid ligase, wherein the composition comprises at least two nucleic acid monomers which are partly complementary to each other and are independently selected from the group consisting of a nucleic acid, a nucleic acid derivative, a modified nucleic acid, a compound capable of binding to a nucleic acid in a complementary manner and a mixture thereof, one of the nucleic acid monomers has a moiety that constitutes a cohesive protruding end and a complementary nucleotide sequence moiety that can bind t at least one of the other nucleic acid monomers to form a double strand, and the composition contains no nucleic acid ligase; and a nucleic acid gel produced using the composition.
申请公布号 JP6083571(B2) 申请公布日期 2017.02.22
申请号 JP20130511034 申请日期 2012.04.19
申请人 国立大学法人京都大学 发明人 西川 元也;高橋 有己;高倉 喜信
分类号 A61K47/30;A61K39/39;C12N15/09 主分类号 A61K47/30
代理机构 代理人
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