摘要 |
The invention concerns a method for preparing a fluorinated compound of formula: (III) R2-(SO2)-NX-(SO2)-F comprising: (a) a first step for obtaining the chlorinated compound of formula: (II) R1-(SO2)-NX-(SO2)-Cl; said first step comprising reacting the sulphonamide of formula: (I) R0-(SO2)-NH2 with sulphuric acid and a chlorinating agent; and (b) a second step for obtaining the fluorinated compound of formula (III), said second step comprising reacting the chlorinated compound of formula (II) with anhydrous hydrofluoric acid in at least one organic solvent; in which: -X represents either a hydrogen atom or a monovalent cation M; -R1 represents an electron-withdrawing group having a positive Hammett parameter σp; -if R1 represents Cl, R0 represents OH; if not, R0 is identical to R1; and -if R1 represents Cl, R2 represents F; if not, R2 is identical to R1. |