发明名称 NOVEL 20(S)-SULFONYLAMIDINE DERIVATIVES OF CAMPTOTHECIN AND THE USE THEREOF AS A POTENT ANTITUMOR AGENT
摘要 The present invention is related to novel 20-sulfonylamidine derivatives of camptothecin (1), method of synthesizing the same, and use thereof as an antitumor agent, for examples an antitumor agent for treating nasopharyngeal, lung, breast or prostate cancer.
申请公布号 EP3049419(A4) 申请公布日期 2017.02.22
申请号 EP20140848297 申请日期 2014.09.26
申请人 China Medical University Hospital 发明人 QIAN, Keduo;LIU, Ying-Qian;GOTO, Masuo;YANG, Liu;ZHANG, Zhi-Jun;TENG, Che-Ming;WU, Tian-Shung;WANG, Chih-Ya;HUNG, Hsin-Yi;CHANG, Ling-Chu;KUO, Sheng-Chu;WU, Yang-Chang;PAN, Shiow-Lin;HSU, Chung Y.;SHYU, Woei-Cherng;LIN, Chen-Huan;LEE, Kuo-Hsiung;SHYU, Woei-Cherng;YANG, Xiaoming;ZHAO, Yong-Long;WANG, Mei-Juan
分类号 C07D491/12;A61K31/4745;A61K35/00;A61P35/00;C07F9/6561 主分类号 C07D491/12
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