| 发明名称 |
IGF-1R SIGNALING PATHWAY INHIBITORS USEFUL IN THE TREATMENT OF NEURODEGENERATIVE DISEASES |
| 摘要 |
The present invention provides compounds acting as Insulin/IGF signaling modulators useful in the treatment of neurodegenerative diseases and disorders. The invention provides pharmaceutical compositions including such compounds, and methods of using these compounds and compositions for the treatment of neurodegenerative diseases, in particular neurodegenerative diseases caused by proteotoxicity such as Alzheimer's disease. |
| 申请公布号 |
EP3021944(A4) |
申请公布日期 |
2017.02.22 |
| 申请号 |
EP20140825966 |
申请日期 |
2014.07.13 |
| 申请人 |
Yissum Research Development Company of The Hebrew University of Jerusalem Ltd. |
发明人 |
REUVENI, Hadas;COHEN, Ehud;LEVITSKI, Alexander;BEN-SASSON, Shmuel |
| 分类号 |
A61K31/165;A61K31/5415;A61P25/00;A61P25/28;C07C327/44;C07D277/36 |
主分类号 |
A61K31/165 |
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