发明名称 |
Derivados aminopropiónicos sustituidos como inhibidores de neprilisina |
摘要 |
The present invention provides a compound of formula I';
or a pharmaceutically acceptable salt thereof, wherein R 1 , R 2 , R 3 , R 5 , B 1 , X and n are defined herein. The invention also relates a method for manufacturing the compounds of the invention, and its therapeutic uses. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition. |
申请公布号 |
ES2602902(T3) |
申请公布日期 |
2017.02.22 |
申请号 |
ES20130151795T |
申请日期 |
2010.05.26 |
申请人 |
Novartis AG |
发明人 |
Coppola, Gary Mark;Iwaki, Yuki;Karki, Rajeshri Ganesh;Kawanami, Toshio;Ksander, Gary Michael;Mogi, Muneto;Sun, Robert |
分类号 |
C07D213/82;A61K31/21;A61K31/435;C07C233/47;C07D239/36;C07D261/18;C07D271/06 |
主分类号 |
C07D213/82 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|