发明名称 |
ANALYTICAL METHOD FOR DETECTING SULFATED OLIGOSACCHARIDES |
摘要 |
The present invention describes an analytical method for detecting and quantitating poly-sulfated oligosaccharides, including Fondaparinux sodium, using hydrophilic interaction ultra-performance liquid chromatography (HILIC-UPLC) coupled with a charged aerosol detector (CAD) or a mass spectrometer (MS). This analytical method provides in-process control in a total synthesis of highly sulfated oligosaccharides by separation, quantification and mass identification. Systems and conditions utilizing such methods are also provided. |
申请公布号 |
EP3019861(A4) |
申请公布日期 |
2017.02.22 |
申请号 |
EP20130888999 |
申请日期 |
2013.07.11 |
申请人 |
Scinopharm Taiwan, Ltd. |
发明人 |
CHAO, Helen;WANG, ChungYao;HUANG, Imin;WU, ChiaYen;CHIANG, YungTe |
分类号 |
G01N30/88;B01D15/30;C08B37/00;G01N30/72 |
主分类号 |
G01N30/88 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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