Applicators for controlled in situ delivery of therapeutic compositions and implants, methods of fabrication and use

摘要

The present disclosure relates to applicators designed for controlled in situ delivery of therapeutic films or depots during a surgical procedure.

主权项

1. An applicator for use in surgical procedures comprising:
a base including a proximal and distal ends and defining an elongated passage extending therebetween, a reservoir for receiving a composition, a mechanism for aerosolizing the composition, the mechanism positioned between the reservoir and the base, and, a polymerizing member positioned within the base on a length of the elongated passage, wherein the polymerizing member is configured to polymerize the composition as the composition passes through the applicator and the polymerizing member comprises at least one of an ultraviolet light emitting diode, infrared light emitting diode, ultraviolet bulb, infrared bulb, or microwave generator.