发明名称 Procedure for the obtainment of fatty acids of pharmacological and nutritional interest
摘要 This invention refers to a procedure for obtaining fatty acids of pharmacological and nutritional interest that comprises the steps of feeding a gas comprising CO2 into a reactor that contains a culture that comprises at least one species of microalgae capable of photosynthesis, the process of photosynthesis by the species of microalgae from the CO2 supplied, producing a biomass that contains a general formula (I) compound:; extraction of the general formula (I) compound from the biomass obtained and concentration and/or purification of this compound.
申请公布号 US9573875(B2) 申请公布日期 2017.02.21
申请号 US201013805421 申请日期 2010.06.23
申请人 Stroïazzo Mougin Bernard A. J. 发明人 Stroïazzo Mougin Bernard A. J.
分类号 A23L33/12;C07C57/03;A61K31/201;A61K31/202;C12P7/64;A61K45/06 主分类号 A23L33/12
代理机构 Ladas & Parry LLP 代理人 Ladas & Parry LLP
主权项 1. Procedure for obtaining fatty acids of pharmacological and nutritional interest comprising the steps of: a) feeding a gas or mixture of gases comprising CO2 into a reactor containing a culture that comprises at least one species of microalgae capable of photosynthesis; b) photosynthesis by the species of microalgae using the CO2 supplied, producing a biomass containing the general formula (I) compound:wherein: A and X are equal or different independently and are selected from alkyl C3-C10, alkenyl C1-C10, cycloalkyl C1-C7 or any substituted or unsubstituted aryl group; n is an integer from 1 to 10; R is selected from H, a hydroxyl group, alkyl C1-C4, alkenyl C1-C3, cycloalkyl C3-C7 or any substituted or unsubstituted aryl group; W is selected from the group consisting of a hydroxyl group, a glycerol molecule bound to an additional general formula (I) compound forming a diglyceride, or a glycerol molecule bound to two additional general formula (I) compounds forming a triglyceride; and their salts, preferably any pharmaceutically acceptable salt, solvates and their prodrugs; c) extraction of the general formula (I) compound from the biomass obtained in step b); and d) concentration and/or purification of the general formula (I) compound from the extract obtained in step c);characterised in that, after the photosynthesis step, between 5 and 100% of the culture is removed from the reactor, which is then separated in a solid fraction that contains biomass, which biomass subsequently undergoes the step of extracting the general formula (I) compound and a liquid phase fraction that contains carbonates and/or bicarbonates, which are separated from the liquid fraction, after which the liquid fraction substantially free of carbonates and/or bicarbonates is then returned at least partially to the reactor.
地址 Alicante ES