发明名称 MicroRNA signatures in human ovarian cancer
摘要 Described herein are methods and compositions for the diagnosis, prognosis and treatment of ovarian cancer. Also described are methods of identifying anti-cancer agents.
申请公布号 US9574239(B2) 申请公布日期 2017.02.21
申请号 US201414485995 申请日期 2014.09.15
申请人 The Ohio State University Research Foundation 发明人 Croce Carlo M.
分类号 G01N33/574;C12Q1/68;A61K31/7088 主分类号 G01N33/574
代理机构 MacMillan, sobanski & Todd, LLC 代理人 MacMillan, sobanski & Todd, LLC
主权项 1. A method to measure miRNA in a subject, the method consisting of: receiving a test sample extracted from the subject, the test sample comprising ovarian tissue; receiving a control sample extracted from the subject, the control sample comprising normal ovarian tissue, and measuring levels of miRNA gene products in the test sample and in the control sample, wherein the measuring levels of miRNA gene products in the test sample and in the control sample consists of measuring levels of miR-200a, miR-200c, miR-204, miR-101-1, miR-214, miR-34c, miR-374, miR-195, miR-215, miR-28, miR-29a, and miR-133b.
地址 Columbus OH US