Nurotoxic sterol glycosides

摘要

The invention relates to compositions for use in animal models of neurodegenerative disease and methods therefor. More particularly, the invention relates to the use of neurotoxic sterol glycosides or neurotoxic glycolipids, or combinations thereof, in animal models of neurodegenerative disease. Neurotoxicity-modulating chromenols can also be used in these animal models in combination with the neurotoxic sterol glycosides or neurotoxic glycolipids, or combinations thereof.

主权项

1. A method of monitoring a neurodegenerative disease in a non-human animal, the method comprising the steps of
administering to the non-human animal a composition comprising a neurotoxic compound, wherein the compound is stigmasterol glucoside; and monitoring the neurodegenerative disease in the non-human animal.