发明名称 |
anticorpo ou seu fragmento que possui reatividade imunológica com um polipeptídeo caprin-1, composição farmacêutica e combinação farmacêutica de tratamento e/ou prevenção de câncer, dna e método de tratamento e/ou prevenção de câncer |
摘要 |
This invention provides an antibody targeting a cancer antigenic protein specifically expressed on the surface of cancer cells and use thereof as a therapeutic and/or preventive agent for cancer. More specifically, the present invention provides an antibody, or a fragment thereof which has immunological reactivity with a partial CAPRIN-1 polypeptide consisting of the amino acid sequence shown by SEQ ID NO: 5 or an amino acid sequence having 80% or higher sequence identity to the amino acid sequence, and a pharmaceutical composition for treatment and/or prevention of cancer comprising the same as an active ingredient. |
申请公布号 |
BR112014002608(A2) |
申请公布日期 |
2017.02.21 |
申请号 |
BR20141102608 |
申请日期 |
2012.08.03 |
申请人 |
TORAY INDUSTRIES, INC |
发明人 |
FUMYOSHI OKANO;SHINICHI KOBAYASHI;TAKANORI SAITO;YOSHITAKA MINAMIDA |
分类号 |
A61K39/395;A61P35/00;C07K16/30;C12N15/09;C12P21/08 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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