Subchondral treatment of joint pain of the spine

摘要

Methods for altering the natural history of degenerative disc disease and osteoarthritis of the spine are proposed. The methods focus on the prevention, or delayed onset or progression of, subchondral defects such as bone marrow edema or bone marrow lesion, and subchondral treatment to prevent the progression of osteoarthritis or degenerative disc disease in the spine and thereby treat pain.

主权项

1. A method of treating a facet in a spinal segment of a patient, the method comprising:
identifying bone marrow edema in a facet in a spinal segment of a patient so as to establish targeted bone marrow edema for receiving treatment, the targeted bone marrow edema occurring in a subchondral region of the facet, the subchondral region of the facet occurring under an articular surface of the facet, wherein said identifying includes identifying with MRI; creating, in the facet that contains the targeted bone marrow edema in the subchondral region, a subchondral injection path to an area in and/or adjacent to the targeted bone marrow edema for injecting an injectable bone filling material into said area for reinforcing bone located in the targeted bone marrow edema, wherein said creating preserves an existing condition of the articular surface of the facet, and wherein said creating is conducted without further creating a void in or adjacent to the targeted bone marrow edema; and injecting an injectable and curable bone filling material into said area via the subchondral injection path, wherein the injectable bone filling material is a bone reinforcing material that is left in the area for hardening in the area so as to form, in situ, a bone reinforcing member for reinforcing bone located in the targeted bone marrow edema, wherein the injectable bone filling material is left in the area without also delivering and leaving a structural implant device in and/or adjacent to the targeted bone marrow edema in addition to the injectable bone filling material.