发明名称 METHOD FOR PREPARING BROWN ADIPOCYTE
摘要 The present invention addresses the problem of providing: a brown adipocyte; a method for preparing the brown adipocyte; a transplantation material containing a brown adipocyte; a prophylactic or therapeutic agent for various diseases and conditions, which contains a brown adipocyte; and a use. As a means for solving the problem, a method for preparing a brown adipocyte is provided, said method being characterized by comprising culturing a differentiated somatic cell from a mammal in a culture medium in the presence of at least one compound selected from the group consisting of (1) a TGFβ/SMAD pathway inhibitor, (2) a casein kinase 1 inhibitor, (3) a cAMP inducer and (4) an MEK/ERK pathway inhibitor to convert the somatic cell into a brown adipocyte.
申请公布号 WO2017026462(A1) 申请公布日期 2017.02.16
申请号 WO2016JP73356 申请日期 2016.08.08
申请人 KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION 发明人 YAMAMOTO, Kenta;KISHIDA, Tsunao;YAMAMOTO, Toshiro;MAZDA, Osam
分类号 C12N5/077;A61K35/35;A61L27/00;A61P3/00;A61P3/10 主分类号 C12N5/077
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