发明名称 |
METHOD FOR PREPARING BROWN ADIPOCYTE |
摘要 |
The present invention addresses the problem of providing: a brown adipocyte; a method for preparing the brown adipocyte; a transplantation material containing a brown adipocyte; a prophylactic or therapeutic agent for various diseases and conditions, which contains a brown adipocyte; and a use. As a means for solving the problem, a method for preparing a brown adipocyte is provided, said method being characterized by comprising culturing a differentiated somatic cell from a mammal in a culture medium in the presence of at least one compound selected from the group consisting of (1) a TGFβ/SMAD pathway inhibitor, (2) a casein kinase 1 inhibitor, (3) a cAMP inducer and (4) an MEK/ERK pathway inhibitor to convert the somatic cell into a brown adipocyte. |
申请公布号 |
WO2017026462(A1) |
申请公布日期 |
2017.02.16 |
申请号 |
WO2016JP73356 |
申请日期 |
2016.08.08 |
申请人 |
KYOTO PREFECTURAL PUBLIC UNIVERSITY CORPORATION |
发明人 |
YAMAMOTO, Kenta;KISHIDA, Tsunao;YAMAMOTO, Toshiro;MAZDA, Osam |
分类号 |
C12N5/077;A61K35/35;A61L27/00;A61P3/00;A61P3/10 |
主分类号 |
C12N5/077 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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